SCHEMBL4433003

SCHEMBL4433003

O=C(Oc1cccnc1)N(SO)N1C(=O)CCC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.44
ALOX15 P16050 2/20 0.44
MAPT P10636 6/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
USP2 O75604 1/20 0.39
CCNC P24863 1/20 0.39
CDK8 P49336 1/20 0.39
MEN1 O00255 2/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2581767 0.73 KMT2A (0.43) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL2581766 0.73 KMT2A (0.43) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL31524305 0.71 RAB9A (0.57) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL10635171 0.71 RAB9A (0.57) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL8128655 0.69 KMT2A (0.51) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL5029189 0.69 L3MBTL1 (0.42) KMT2AALDH1A1KDM4ENPSR1MEN1
SCHEMBL6294601 0.69 KMT2A (0.57) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL4670462 0.68 KMT2A (0.61) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL1466982 0.67 KMT2A (0.56) KMT2AALOX15MAPTALDH1A1KDM4E
SCHEMBL876393 0.67 KMT2A (0.56) KMT2AALOX15MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7494815-B2 Method and apparatus for analyzing compounds with amino group AJINOMOTO CO., INC. (JP) 2009-02-24 US claimed
US-20070269899-A1 METHOD AND APPARATUS FOR ANALYZING COMPOUNDS WITH AMINO GROUP AJINOMOTO CO. INC. (JP) 2007-11-22 US claimed
EP-1750126-A1 METHOD AND APPARATUS FOR ANALYZING AMINOFUNCTIONAL COMPOUND Ajinomoto Co., Inc. (JP) 2007-02-07 EP claimed