SCHEMBL4433305

SCHEMBL4433305

C[Si](C)(C)c1ccccc1NC(N)=O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 4/20 0.45
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP1A2 P05177 2/20 0.44
MAPT P10636 1/20 0.41
GFER P55789 1/20 0.41
MAPK1 P28482 1/20 0.40
ESR2 Q92731 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29840068 0.80 GAA (0.67) POLBGAAKDM4EALDH1A1RECQL
SCHEMBL3928666 0.80 GAA (0.67) POLBGAAKDM4EALDH1A1RECQL
SCHEMBL14145806 0.79 POLB (0.61) POLBCYP1A2MAPTMAPK1NPC1
SCHEMBL30275531 0.74 ALDH1A1 (0.58) POLBGAAKDM4EALDH1A1RECQL
SCHEMBL11016637 0.74 IDO1 (0.35) ALDH1A1RECQLSMN1; SMN2NPC1RAB9A
SCHEMBL26596768 0.73 MEN1 (0.37) POLBGAAKDM4EALDH1A1RECQL
SCHEMBL81434 0.72 POLB (0.75) POLBGAAKDM4EALDH1A1MAPT
SCHEMBL29521664 0.72 POLB (0.75) POLBGAAKDM4EALDH1A1MAPT
SCHEMBL7417077 0.72 GAA (0.57) POLBGAAKDM4EALDH1A1RECQL
SCHEMBL15259585 0.72 KDM4E (0.57) POLBGAAKDM4EALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US claimed
EP-2010386-A2 INTERLAYERS COMPRISING STABLE INFRARED ABSORBING AGENTS Solutia Incorporated (US) 2009-01-07 EP disclosed
US-7405865-B2 Liquid for electrophoretic display, display medium and display device using the same MITSUBISHI PENCIL CO., LTD. (JP) 2008-07-29 US disclosed
US-20070248809-A1 Interlayers Comprising Stable Infrared Absorbing Agents DEUTSCHE BANK TRUST COMPANY AMERICAS, AS COLLATERAL AGENT 2007-10-25 US disclosed
WO-2007121079-A2 INTERLAYERS COMPRISING HYDROLYTICALLY STABLE INFRARED ABSORBING AGENTS SOLUTIA INCORPORATED (US) 2007-10-25 WO disclosed
US-7244376-B2 Hexaboride particles, hexaboride particle dispersion, and article making use of hexaboride particles or hexaboride particle dispersion SUMITOMO METAL MINING CO., LTD. (JP) 2007-07-17 US disclosed
US-20070002427-A1 Liquid for electrophoretic display and display medium and display employing it MITSUBISHI PENCIL CO., LTD. (JP) 2007-01-04 US disclosed
CN-1846165-A Liquid for electrophoretic display, display medium using the same, and display device MITSUBISHI PENCIL CO (JP) 2006-10-11 CN disclosed
EP-1669798-A1 LIQUID FOR ELECTROPHORETIC DISPLAY AND DISPLAY MEDIUM AND DISPLAY EMPLOYING IT Mitsubishi Pencil Co., Ltd. (JP) 2006-06-14 EP disclosed
US-6972314-B2 OH-containing polysiloxane; carbodiimide; organosilicon crosslinking agent; cured rubber with a higher elongation percentage and improved heat, oil and chemical resistance; automobile applications HENKEL CORPORATION (US) 2005-12-06 US disclosed
WO-2004033573-A9 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORP (US) 2005-01-13 WO disclosed
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US disclosed
US-20040127669-A1 Silicone resin composition HENKEL LOCTITE CORPORATION 2004-07-01 US disclosed
WO-2004033573-A1 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2004-04-22 WO disclosed
US-20040068036-A1 Flexible emissive coatings for elastomer substrates LORD CORPORATION 2004-04-08 US disclosed
US-6400492-B1 Electrophoretic display liquid, and electrophoretic display medium, method and device using the liquid RICOH COMPANY LIMITED (JP) 2002-06-04 US disclosed
EP-0661358-B1 COATING RESIN COMPOSITION ASAHI GLASS CO LTD (JP) 2000-03-29 EP disclosed
US-5895713-A SILANE SURFACTANT, TETRAALKOXYSILANE OR OLIGOMER ASAHI GLASS COMPANY LTD. (JP) 1999-04-20 US disclosed
US-5532304-A WEATHERPROOFING ASAHI GLASS COMPANY LTD. (JP) 1996-07-02 US disclosed
EP-0661358-A1 COATING RESIN COMPOSITION ASAHI GLASS COMPANY LTD. (JP) 1995-07-05 EP disclosed