Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389562 | 0.89 | GPR119 (0.71) | GPR119CYP2C9 | |
| SCHEMBL390823 | 0.84 | GPR119 (0.76) | GPR119CYP2C9 | |
| SCHEMBL4263519 | 0.84 | GPR119 (0.75) | GPR119CYP2C9 | |
| SCHEMBL1897313 | 0.82 | GPR119 (1.00) | GPR119CYP2C9 | |
| SCHEMBL12241555 | 0.81 | GPR119 (0.84) | GPR119CYP2C9 | |
| SCHEMBL390647 | 0.80 | GPR119 (0.70) | GPR119CYP2C9 | |
| SCHEMBL389518 | 0.79 | GPR119 (0.76) | GPR119CYP2C9 | |
| SCHEMBL4256534 | 0.79 | GPR119 (0.64) | GPR119CYP2C9 | |
| SCHEMBL16503907 | 0.77 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL288373 | 0.77 | GPR119 (0.58) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758565-B2 | Method of identifying GLP-1 secretagogues | ARENA PHARM INC (US) | 2012-11-14 | — | — | EP | disclosed |
| EP-1758565-B1 | Method of identifying GLP-1 secretagogues | ARENA PHARM INC (US) | 2009-05-13 | — | — | EP | disclosed |