Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981976 | 0.89 | KMT2A (0.50) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL29392607 | 0.89 | KMT2A (0.50) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL5473 | 0.89 | KMT2A (0.50) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| Ethylene SCHEMBL27728658 | 0.85 | KMT2A (0.47) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| Nitrous Acid SCHEMBL16781801 | 0.81 | SLC2A1 (0.54) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| Nitrous Acid SCHEMBL16781802 | 0.81 | SLC2A1 (0.54) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| Formic Acid SCHEMBL28323292 | 0.81 | SLC2A1 (0.50) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL8466648 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL8141809 | 0.79 | KMT2A (0.45) | ALDH1A1ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL28168986 | 0.79 | KMT2A (0.56) | ALDH1A1ADRA2AADRA2BADRA2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |