SCHEMBL5473

SCHEMBL5473

O=[N+]([O-])c1ccc(Cl)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
LMNA P02545 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 5/20 0.49
ALDH1A1 P00352 4/20 0.49
GAA P10253 2/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
RECQL P46063 1/20 0.49
ADRA2A P08913 2/20 0.49
ADRA2B P18089 2/20 0.49
ADRA2C P18825 2/20 0.49
SLC2A1 P11166 1/20 0.49
MEN1 O00255 3/20 0.47
CYP1A2 P05177 2/20 0.47
ALOX12 P18054 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 1/20 0.46
AGTR1 P30556 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392607 1.00 KMT2A (0.50) KMT2ALMNATDP1MAPTALDH1A1
SCHEMBL27981976 1.00 KMT2A (0.50) KMT2ALMNATDP1MAPTALDH1A1
Ethylene SCHEMBL27728658 0.96 KMT2A (0.47) KMT2ALMNATDP1MAPTALDH1A1
Formic Acid SCHEMBL28323292 0.91 SLC2A1 (0.50) KMT2ALMNATDP1MAPTALDH1A1
Nitrous Acid SCHEMBL16781802 0.91 SLC2A1 (0.54) KMT2ALMNATDP1MAPTALDH1A1
Nitrous Acid SCHEMBL16781801 0.91 SLC2A1 (0.54) KMT2ALMNATDP1MAPTALDH1A1
SCHEMBL8141809 0.89 KMT2A (0.45) KMT2ALMNATDP1MAPTALDH1A1
SCHEMBL28168986 0.89 KMT2A (0.56) KMT2ALMNATDP1MAPTALDH1A1
SCHEMBL4434207 0.89 ALDH1A1 (0.52) KMT2ALMNATDP1MAPTALDH1A1
SCHEMBL11171259 0.84 MAPT (0.61) KMT2ALMNATDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727911-A2 FLUORINATION METHODS, REAGENTS, FLUORINATED COMPOSITIONS, AND METHODS OF MANUFACTURE FLUOROK LIMITED (GB) 2026-04-22 EP claimed
CN-119219892-B Preparation method of medical hydrophilic polyurethane sponge 东莞市奥尼高分子材料科技有限公司 2025-04-01 CN claimed
CN-119684278-A Triphenylamine derivative and preparation method and application thereof 福建理工大学 2025-03-25 CN claimed
CN-119528807-A Pyridyl anti-aging agent and synthetic method and application thereof 山东阳谷华泰化工股份有限公司 2025-02-28 CN claimed
CN-119219892-A Preparation method of medical hydrophilic polyurethane sponge 东莞市奥尼高分子材料科技有限公司 2024-12-31 CN claimed
WO-2024256871-A2 FLUORINATION METHODS, REAGENTS, FLUORINATED COMPOSITIONS, AND METHODS OF MANUFACTURE FLUOROK LIMITED (GB) 2024-12-19 WO claimed
CN-119039347-A Diamino diphosphine tetradentate ligand, preparation method thereof and application thereof in Suzuki cross-coupling reaction 郑州大学 2024-11-29 CN claimed
CN-118562110-B Preparation process and application of modified polyester resin 黄山学院 2024-11-01 CN claimed
US-20240360147-A1 Process for Synthesizing Naphthyridine Derivatives and Intermediates Thereof AMGEN INC. 2024-10-31 US claimed
CN-118562110-A Preparation process and application of modified polyester resin 黄山学院 2024-08-30 CN claimed
CN-101560183-B Method for preparing 5-bromo-2-methylpyridine ZHEJIANG MED XINCHANG PHARM 2011-02-02 CN claimed
US-20090325988-A1 Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2009-12-31 US claimed
WO-2009149139-A1 GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-12-10 WO claimed
CN-101560183-A Method for preparing 5-bromo-2-methylpyridine ZHEJIANG MEDICINE CO LTD (CN) 2009-10-21 CN claimed
CN-1594298-A Pyridine ring containing oxazolidinone compounds and preparation process and application thereof SHANGHAI INST MATERIA MEDICA (CN) 2005-03-16 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-5696282-A CATALYTIC REACTION OF A HYDROGEN SULFIDE OR MERCAPTAN WITH UNSATURATED CARBONYL OR CYANO COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1997-12-09 US claimed
WO-1993016057-A1 1,4-DIALKYLPIPERAZINE DERIVATIVES, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LES LABORATOIRES MERAM (FR) 1993-08-19 WO claimed