Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | MOGAT2 | Q3SYC2 | 8/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188600 | 0.85 | GPR119 (0.58) | — | |
| SCHEMBL3178592 | 0.83 | GPR119 (0.55) | HRH3ESR1ESR2ACACB | |
| SCHEMBL3180742 | 0.82 | HRH3 (0.56) | HRH3ESR1ESR2ACACB | |
| SCHEMBL3178450 | 0.82 | HRH3 (0.55) | HRH3ESR1ESR2MOGAT2CYP2D6 | |
| SCHEMBL3180425 | 0.81 | GPR119 (0.47) | HRH3ESR1ESR2ACACBMOGAT2 | |
| SCHEMBL4437451 | 0.81 | HRH3 (0.53) | HRH3ESR1ESR2ACACBMOGAT2 | |
| SCHEMBL3180488 | 0.81 | HRH3 (0.53) | HRH3ESR1ESR2ACACBMOGAT2 | |
| SCHEMBL3185866 | 0.81 | GPR119 (0.58) | HRH3 | |
| SCHEMBL3182548 | 0.80 | GPR119 (0.65) | HRH3 | |
| SCHEMBL14116821 | 0.80 | HRH3 (0.45) | HRH3ESR1ESR2ACACBMOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |