Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441841 | 0.94 | GNAI3 (0.46) | GNAI3GNAO1GNAI1EPHX1DPP7 | |
| SCHEMBL442276 | 0.94 | DPP7 (0.39) | GNAI3GNAO1GNAI1EPHX1DPP7 | |
| SCHEMBL443152 | 0.81 | ACE2 (0.49) | GNAI3GNAO1GNAI1EPHX1DPP7 | |
| SCHEMBL440464 | 0.81 | ACE2 (0.49) | GNAI3GNAO1GNAI1EPHX1DPP7 | |
| SCHEMBL372894 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR | |
| SCHEMBL14857009 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR | |
| SCHEMBL148882 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR | |
| SCHEMBL149423 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR | |
| SCHEMBL153838 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR | |
| SCHEMBL150597 | 0.78 | EPHX1 (0.59) | EPHX1DPP7PLA2G2AFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |