Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443432 | 0.94 | GNAI3 (0.39) | DPP7EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL441841 | 0.88 | GNAI3 (0.46) | DPP7MMP8EPHX1SMN1; SMN2GNAI3 | |
| SCHEMBL20740917 | 0.77 | KISS1R (0.39) | CYP1A2CYP2C9CYP2C19MMP8SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10992431 | 0.77 | DPP7 (0.45) | DPP7CYP1A2CYP2C9CYP2C19MMP9 | |
| SCHEMBL27247 | 0.77 | ACHE (0.52) | CYP1A2CYP2C19EPHX1ACHEPLA2G2A | |
| SCHEMBL253022 | 0.75 | EPHX1 (0.56) | DPP7EPHX1ACHEPLA2G2A | |
| Hydrochloric Acid SCHEMBL15846376 | 0.75 | ACHE (0.50) | CYP1A2CYP2C19EPHX1ACHEPLA2G2A | |
| Ammonia Solution, Strong SCHEMBL11669840 | 0.75 | ACHE (0.50) | CYP1A2CYP2C19EPHX1ACHEPLA2G2A | |
| SCHEMBL27834646 | 0.75 | ACHE (0.50) | CYP1A2CYP2C19EPHX1ACHEPLA2G2A | |
| SCHEMBL3235398 | 0.75 | ANPEP (0.52) | MMP8SMN1; SMN2CNR1ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |