Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964896 | 1.00 | NPC1 (0.46) | NPC1RAB9AL3MBTL1OPRM1OPRL1 | |
| SCHEMBL5764293 | 0.84 | DRD2 (0.53) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL24582713 | 0.83 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL1000224 | 0.83 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL4442416 | 0.83 | OPRM1 (0.47) | OPRM1OPRL1 | |
| SCHEMBL3208272 | 0.83 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL1150621 | 0.82 | NPC1 (0.46) | NPC1RAB9AL3MBTL1PTGDR2TMEM97 | |
| SCHEMBL31092767 | 0.81 | OPRL1 (0.41) | OPRM1OPRL1 | |
| SCHEMBL31092768 | 0.81 | OPRL1 (0.41) | OPRM1OPRL1 | |
| SCHEMBL7036798 | 0.81 | PTPN1 (0.52) | NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |