Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228325 | 0.98 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL6245526 | 0.91 | — | — | |
| SCHEMBL17204390 | 0.88 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL8429090 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL9701471 | 0.84 | SMN1; SMN2 (0.78) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL10587847 | 0.84 | ALDH1A1 (0.83) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL7553441 | 0.83 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL4154162 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL9337868 | 0.80 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL28668503 | 0.80 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137187-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | Inovacia AB (SE) | 2009-12-30 | — | — | EP | disclosed |
| US-20080255153-A1 | New compounds | BIOVITRUM AB (PUBL) (SE) | 2008-10-16 | — | — | US | disclosed |
| WO-2008116898-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | BIOVITRUM AB (PUBL) (SE) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255153-A1 | New compounds | SCD, SCD5, FADS2 | SMN1; SMN2 987/4885ALDH1A1 1498/4885HPGD 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.