Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424746 | 0.76 | TPMT (0.38) | HRH4KMT2ALMNATSHRMEN1 | |
| SCHEMBL18360196 | 0.74 | HDAC4 (0.36) | HRH4LMNATSHR | |
| SCHEMBL1179729 | 0.73 | HRH4 (0.33) | HRH4KMT2AMEN1 | |
| SCHEMBL3280184 | 0.73 | HRH4 (0.31) | HRH4TSHR | |
| SCHEMBL12250747 | 0.71 | NOS3 (0.40) | HRH4KMT2ATSHRMEN1 | |
| SCHEMBL18360198 | 0.71 | CA12 (0.45) | KMT2ALMNATSHRMEN1 | |
| SCHEMBL12852890 | 0.70 | LMNA (0.37) | KMT2ALMNAGFERL3MBTL1 | |
| SCHEMBL22637833 | 0.68 | RECQL (0.42) | KMT2ALMNAGFERL3MBTL1TSHR | |
| SCHEMBL22637830 | 0.68 | RECQL (0.42) | KMT2ALMNAGFERL3MBTL1TSHR | |
| SCHEMBL9582046 | 0.65 | HTT (0.42) | KMT2ALMNAGFERL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125797-A1 | AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008114157-A1 | AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-09-25 | — | — | WO | disclosed |