Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190969 | 0.71 | HPGDS (0.33) | HPGDSLTA4H | |
| SCHEMBL1706140 | 0.69 | LTA4H (0.35) | HPGDSLTA4H | |
| SCHEMBL2469949 | 0.69 | NOTUM (0.38) | — | |
| SCHEMBL100765 | 0.68 | HPGDS (0.46) | HPGDSLTA4H | |
| SCHEMBL611280 | 0.67 | HPGDS (0.41) | HPGDSLTA4H | |
| SCHEMBL7376054 | 0.65 | HPGDS (0.40) | HPGDSLTA4H | |
| SCHEMBL4015828 | 0.65 | HPGDS (0.36) | HPGDSLTA4H | |
| SCHEMBL3953551 | 0.64 | HPGDS (0.38) | HPGDSLTA4H | |
| SCHEMBL5756567 | 0.63 | — | — | |
| SCHEMBL1457635 | 0.63 | PDPK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125748-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | AstraZeneca AB (SE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008075068-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| WO-2004093860-A1 | INHIBITORS OF SARS RELATED CORONAVIRUS PROTEINASE | PFIZER INC. (US) | 2004-11-04 | — | — | WO | disclosed |