Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29299508 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL14100030 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL1165366 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL1133814 | 0.83 | — | — | |
| SCHEMBL13223389 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL24220960 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL7744888 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL3967181 | 0.83 | SLC6A9 (0.40) | MEN1KMT2ACYP1A2CYP2D6RAB9A | |
| SCHEMBL5090586 | 0.80 | FDPS (0.42) | FDPSMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL22821444 | 0.79 | SLC6A9 (0.36) | MEN1KMT2ACYP2D6RAB9ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121137-A1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075005-A1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |