SCHEMBL4435388

SCHEMBL4435388

Cc1cc(C)cc(O[Zr](Cl)(Cl)Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.32
CYP2C9 P11712 1/20 0.32
ACHE P22303 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591586 0.74 ACHE (0.48) ALDH1A1TSHRCYP3A4TDP1POLB
SCHEMBL458268 0.67 ALDH1A1 (0.67) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL145855 0.65 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL29378528 0.65 ALDH1A1 (0.64) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL12378007 0.65 ALDH1A1 (0.64) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL13317292 0.65 ALDH1A1 (0.64) ALDH1A1TSHRCYP3A4MAPK1TDP1
Phosphine SCHEMBL22361930 0.65 ALDH1A1 (0.64) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL26115 0.65
SCHEMBL341533 0.65 ALDH1A1 (0.67) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL22423651 0.63 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0818472-B2 Cyclic olefin copolymers, compositions and molded articles comprising the copolymers IDEMITSU KOSAN CO (JP) 2009-07-29 EP disclosed
EP-0818472-B1 Cyclic olefin copolymers, compositions and molded articles comprising the copolymers IDEMITSU KOSAN CO (JP) 2001-08-16 EP disclosed
EP-0504418-B2 PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER AND CYCLOOLEFIN COPOLYMERS IDEMITSU KOSAN CO (JP) 2001-06-13 EP disclosed
EP-0504418-B1 PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER AND CYCLOOLEFIN COPOLYMERS IDEMITSU KOSAN CO (JP) 1998-05-13 EP disclosed
EP-0818472-A2 Cyclic olefin copolymers, compositions and molded articles comprising the copolymers IDEMITSU KOSAN CO., LTD. (JP) 1998-01-14 EP disclosed
US-5693728-A Process for producing cyclic olefin based polymers IDEMITSU KOSAN CO., LTD. (JP) 1997-12-02 US disclosed
US-5648443-A Cyclic olefin copolymers, compositions and molded articles comprising the copolymers IDEMITSU KOSAN CO., LTD. (JP) 1997-07-15 US disclosed
US-5629398-A HOMO- OR COPOLYMERIZE WITH OLEFIN USING CATALYST CONTAINING TRANSITION METAL COMPOUND COMPLEXING WITH ANOTHER COMPOUND AND ORGANOALUMINUM COMPOUND; UNIQUE PHYSICAL PROPERTIES IDEMITSU KOSAN CO., LTD. (JP) 1997-05-13 US disclosed
EP-0504418-A1 PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER, CYCLOOLEFIN COPOLYMER, AND COMPOSITION AND MOLDING PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-23 EP disclosed