Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 4/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428559 | 0.93 | FPR1 (0.35) | FPR1FPR2KMT2ACASP1GPR88 | |
| SCHEMBL4434290 | 0.89 | FPR1 (0.39) | FPR1KMT2ACASP1GPR88 | |
| SCHEMBL4426400 | 0.89 | CYP26A1 (0.38) | FPR1CYP26A1GPR88 | |
| SCHEMBL8506622 | 0.87 | CTSA (0.40) | FPR1CYP26A1 | |
| SCHEMBL4435400 | 0.87 | CTSA (0.40) | FPR1CYP26A1 | |
| SCHEMBL4435399 | 0.87 | CTSA (0.40) | FPR1CYP26A1 | |
| SCHEMBL4427187 | 0.87 | MMP2 (0.38) | FPR1CASP1 | |
| SCHEMBL7429087 | 0.87 | MMP2 (0.38) | FPR1CASP1 | |
| SCHEMBL6759875 | 0.86 | FPR1 (0.43) | FPR1P2RX3FPR2KMT2ACASP1 | |
| SCHEMBL4434296 | 0.86 | FPR1 (0.36) | FPR1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |