SCHEMBL4435671

SCHEMBL4435671

Cc1cc(C)c(-c2nc(-c3ccc(O)cc3O)nc(-c3ccc(O)cc3O)n2)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 6/20 0.42
ESR1 P03372 5/20 0.42
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
NPC1 O15118 2/20 0.39
GPR55 Q9Y2T6 2/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8908993 0.87 ESR2 (0.38) ESR2ESR1GAAMGAMSI
SCHEMBL29358205 0.84 ESR2 (0.47) ESR2ESR1GAAMGAMSI
SCHEMBL29350280 0.84 ESR2 (0.47) ESR2ESR1GAAMGAMSI
SCHEMBL39158 0.84 ESR2 (0.47) ESR2ESR1GAAMGAMSI
SCHEMBL580855 0.84 ESR2 (0.47) ESR2ESR1GAAMGAMSI
SCHEMBL9743456 0.81 ESR2 (0.46) ESR2ESR1GAAMGAMSI
SCHEMBL29625130 0.81 NPC1 (0.52) ESR2ESR1GAANPC1MAPT
SCHEMBL547889 0.81 NPC1 (0.52) ESR2ESR1GAANPC1MAPT
SCHEMBL28020448 0.81 ALOX5 (0.41) ESR2ESR1GAAMGAMSI
SCHEMBL27542279 0.81 ALOX5 (0.41) ESR2ESR1GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865620-B2 Heat-sensitive coating compositions based on resorcinyl triazine derivatives DATALASE, LTD. (GB) 2014-10-21 US disclosed
US-8865620-B2 Heat-sensitive coating compositions based on resorcinyl triazine derivatives DATALASE, LTD. (GB) 2014-10-21 US disclosed
US-8865620-B2 Heat-sensitive coating compositions based on resorcinyl triazine derivatives DATALASE, LTD. (GB) 2014-10-21 US disclosed
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES DATALASE LTD 2011-12-22 US disclosed
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES DATALASE LTD 2011-12-22 US disclosed
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES DATALASE LTD 2011-12-22 US disclosed
EP-2121853-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (DE) 2009-11-25 EP disclosed
WO-2008110487-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (CH) 2008-09-18 WO disclosed
WO-2008110487-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (CH) 2008-09-18 WO disclosed
US-6242598-B1 NUCLEOPHILIC DISPLACEMENT OF A CYANURIC CHLORIDE ATOM WITH A PHENOLIC MOIETY, A FRIEDEL-CRAFTS REACTION USING A LEWIS ACID, AND REPLACING THE PHENOLIC MOIETY WITH RESORINOL USING A LEWIS ACID OR A PROTIC ACID CATALYSTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-05 US disclosed
WO-2000014126-A1 PHOTOSTABLE CHROMOPHORE SYSTEM CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-16 WO disclosed
EP-0941989-A2 Process for the preparation of 2,4-diaryl-6-o-hydroxyphenyl-1,3,5-triazine derivatives in the presence of a protic acid catalyst Ciba SC Holding AG (CH) 1999-09-15 EP disclosed
US-5869588-A UV ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 US disclosed
US-5686233-A PHOTOGRAPHIC FILM STABILIZER CIBA-GEIGY CORPORATION (US) 1997-11-11 US disclosed
US-5672704-A ULTRAVIOLET RADIATION STABILIZERS CIBA-GEIGY CORPORATION 1997-09-30 US disclosed
US-5597854-A PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1997-01-28 US disclosed
US-5538840-A SILVER HALIDE EMULSIONS AND POLYMERS ON SUBSTRATES WITH TRIAZINE PHENOLS CIBA-GEIGY CORPORATION (US) 1996-07-23 US disclosed
EP-0711804-A2 Latent light stabilizers CIBA-GEIGY AG (CH) 1996-05-15 EP disclosed
EP-0706083-A1 Photographic recording material containing an UV-absorber CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES OR10J3, NR3C2, NR1H2 ESR2 476/4885ESR1 495/4885GAA 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.