Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625130 | 1.00 | NPC1 (0.52) | NPC1ALOX5TYRESR1ESR2 | |
| Water SCHEMBL8683475 | 0.97 | NPC1 (0.50) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL18913903 | 0.89 | SMN1; SMN2 (0.57) | NPC1ALOX5ESR1ESR2MAPT | |
| SCHEMBL5703463 | 0.89 | NPC1 (0.44) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL4981440 | 0.89 | MEN1 (0.50) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL14070316 | 0.89 | HSD17B10 (0.50) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL6444289 | 0.89 | MEN1 (0.50) | NPC1ALOX5TYRESR1ESR2 | |
| Phenol SCHEMBL7138886 | 0.89 | ALOX5 (0.57) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL22207213 | 0.89 | NPC1 (0.69) | NPC1ALOX5TYRESR1ESR2 | |
| SCHEMBL4438569 | 0.86 | ESR1 (0.46) | NPC1ALOX5TYRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276672-A | A kind of composite material and preparation method for computer cabinet shell | 合肥思博特软件开发有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-108178909-A | A kind of road lighting LED lamp cover composite material and preparation method thereof | 合肥安力电力工程有限公司 | 2018-06-19 | — | — | CN | claimed |
| JP-4743971-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| EP-2267523-A2 | Stabilized electrochromic media | BASF SE (DE) | 2010-12-29 | — | — | EP | claimed |
| US-7595011-B2 | One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-29 | — | — | US | claimed |
| EP-1999195-A1 | METHOD FOR INCORPORATING ADDITIVES INTO POLYMERS | Ciba Holding Inc. (CH) | 2008-12-10 | — | — | EP | claimed |
| US-7332105-B2 | Synergistic UV absorber combination | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-02-19 | — | — | US | claimed |
| US-7326740-B2 | Natural products composites | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-02-05 | — | — | US | claimed |
| WO-2007128672-A1 | SUBSTITUTED HEXAHYDRO-1,4-DIAZEPIN-5-ONES AND COMPOSITIONS STABILIZED THEREWITH | CIBA HOLDING INC. (CH) | 2007-11-15 | — | — | WO | claimed |
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | WOOD MERVIN G | 2007-11-08 | — | — | US | claimed |
| US-20020194776-A1 | Candle wax stabilized with imidazolidines | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-26 | — | — | US | claimed |
| US-20020189155-A1 | Candle wax stabilized with s-triazines/hals | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-19 | — | — | US | claimed |
| EP-1263833-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | claimed |
| WO-2002079313-A1 | STABILIZED CANDLE WAX | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | claimed |
| WO-2002079314-A1 | CANDLE WAX STABILIZED WITH S-TRIAZINES/HALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | claimed |
| EP-1181338-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, HIGH EXTINCTION, PHOTOSTABLE HYDROXYPHENYL-S-TRIAZINE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | Ciba SC Holding AG (CH) | 2002-02-27 | — | — | EP | claimed |
| WO-2001062821-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-30 | — | — | WO | claimed |
| US-6225384-B1 | FOR SOLAR CONTROL FILMS, FILMS AND GLAZINGS, ULTRAVIOLET RADIATION ABSORBING GLASSES AND GLASS COATINGS, WINDSCREENS, RETROREFLECTIVE SHEETINGS AND SIGNS, SOLAR REFLECTORS, AND OPTICAL FILMS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-05-01 | — | — | US | claimed |
| WO-2000066675-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, HIGH EXTINCTION, PHOTOSTABLE HYDROXYPHENYL-s-TRIAZINE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (DE) | 2000-11-09 | — | — | WO | claimed |
| EP-0863145-A2 | Sunscreen compositions | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | CRY1, GPX4, CAND1 | NPC1 2335/4885ALOX5 645/4885TYR 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.