Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111411 | 0.89 | CYP19A1 (0.43) | TAAR1SIGMAR1 | |
| SCHEMBL4015441 | 0.84 | KCNH2 (0.36) | TAAR1MAOB | |
| SCHEMBL4017121 | 0.84 | HTR1D (0.37) | TAAR1 | |
| SCHEMBL4023686 | 0.84 | HTR3A (0.37) | TAAR1 | |
| SCHEMBL12098835 | 0.83 | GBA1 (0.46) | TAAR1 | |
| SCHEMBL72389 | 0.83 | GBA1 (0.46) | TAAR1 | |
| SCHEMBL4016068 | 0.82 | MAPK1 (0.43) | TAAR1MAOAMAOB | |
| SCHEMBL4839660 | 0.80 | REN (0.43) | TAAR1MAOB | |
| SCHEMBL3154456 | 0.74 | SLC18A2 (0.50) | TAAR1SLC18A2 | |
| SCHEMBL1968440 | 0.72 | SLC18A2 (0.49) | TAAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322844-A | Cardiovascular disorders, antiinflammatory agents, antiallergens | GODECKE AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | claimed |
| EP-2118110-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008112851-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |
| US-5322844-A | Cardiovascular disorders, antiinflammatory agents, antiallergens | GODECKE AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | disclosed |
| US-5185352-A | Treating or preventing cardiovascular disorders | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |