SCHEMBL4436212

SCHEMBL4436212

O=C1OC=CCC1C1CCCC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938530 0.68 MAPT (0.33) MAPTMEN1ALDH1A1KMT2AHPGD
SCHEMBL10937868 0.67 MAPT (0.33) MAPTALDH1A1KMT2AHPGD
SCHEMBL10935590 0.67 MAPT (0.33) MAPTALDH1A1KMT2AHPGD
SCHEMBL10996290 0.66
SCHEMBL2299221 0.65 MAPT (0.31) MAPT
SCHEMBL9813669 0.63 ALDH1A1 (0.33) MAPTMEN1ALDH1A1KMT2AHPGD
SCHEMBL3950457 0.61
SCHEMBL9813666 0.61 MAPT (0.33) MAPTMEN1ALDH1A1KMT2AHPGD
SCHEMBL31547150 0.61 ALDH1A1 (0.32) MAPTMEN1ALDH1A1KMT2AHPGD
SCHEMBL29526579 0.61 ALDH1A1 (0.31) ALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070154490-A1 Sequence Of Reverse Transcriptase Gene And Method Of Use FUDAN UNIVERSITY (CN) 2007-07-05 US claimed
US-8748087-B2 Sequence of reverse transcriptase gene and method of use FUDAN UNIVERSITY (CN) 2014-06-10 US disclosed
EP-2463390-A1 Methodology for analysis of sequence variations within the HCV NS5B genomic region Innogenetics N.V. (BE) 2012-06-13 EP disclosed
EP-2463389-A1 Methodology for analysis of sequence variations within the HCV NS5B genomic region Innogenetics N.V. (BE) 2012-06-13 EP disclosed
US-20090325145-A1 METHODOLOGY FOR ANALYSIS OF SEQUENCE VARIATIONS WITHIN THE HCV NS5B GENOMIC REGION INNOGENETICS N.V. (BE) 2009-12-31 US disclosed
EP-2121990-A2 METHODOLOGY FOR ANAYSIS OF SEQUENCE VARIATIONS WITHIN THE HCV NS5B GENOMIC REGION Innogenetics N.V. (BE) 2009-11-25 EP disclosed
WO-2008046922-A2 METHODOLOGY FOR ANAYSIS OF SEQUENCE VARIATIONS WITHIN THE HCV NS5B GENOMIC REGION INNOGENETICS N.V. (BE) 2008-04-24 WO disclosed
US-20070154490-A1 Sequence Of Reverse Transcriptase Gene And Method Of Use FUDAN UNIVERSITY (CN) 2007-07-05 US disclosed