Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813666 | 0.98 | MAPT (0.33) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL728783 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8815894 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL47305 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8444553 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13253702 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6383420 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16116751 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL20715180 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13618315 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219199-B1 | METHOD FOR PREPARATION OF LACTONES | COULSTON INTERNATIONAL CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4772728-A | AND ALDEHYDE | ANGUS CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0219199-A1 | Method for preparation of lactones | COULSTON INTERNATIONAL CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |