SCHEMBL443625

SCHEMBL443625

COc1ccc2cccc(OC)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
CYP2A6 P11509 2/20 0.57
NQO1 P15559 1/20 0.55
MTNR1A P48039 5/20 0.53
HTR2A P28223 2/20 0.53
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
MAPT P10636 2/20 0.52
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30088510 1.00 CYP1A2 (0.57) CYP1A2CYP2A6NQO1MTNR1AHTR2A
SCHEMBL7453747 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL31340104 0.87 CYP1A2 (0.52) CYP1A2CYP2A6NQO1MTNR1AHTR2A
SCHEMBL29703104 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL6939973 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL443271 0.84 CYP1A2 (0.57) CYP1A2CYP2A6NQO1MTNR1ABCHE
SCHEMBL29869216 0.84 CYP1A2 (0.57) CYP1A2CYP2A6NQO1MTNR1ABCHE
SCHEMBL15772597 0.84 MTNR1A (0.49) NQO1MTNR1AHTR2ABCHEACHE
SCHEMBL3914262 0.84 HTR2A (0.50) CYP1A2CYP2A6MTNR1AHTR2ABCHE
SCHEMBL7847800 0.84 NPSR1 (0.50) CYP1A2CYP2A6MTNR1AHTR2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299636-A COMPOSITE MODIFIED DOUBLE BASE HERCULES INCORPORATED (US) 1981-11-10 US claimed
US-20250304595-A1 Electroactive Compounds LG CHEM, LTD. (KR) 2025-10-02 US disclosed
US-12384796-B2 Electroactive compounds LG CHEM, LTD. (KR) 2025-08-12 US disclosed
WO-2024024490-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2024-02-01 WO disclosed
WO-2023238920-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM TO REDUCE ENVIRONMENTAL IMPACT 日産化学株式会社 2023-12-14 WO disclosed
WO-2023181960-A1 COMPOSITION FOR FORMING PROTECTIVE FILM 日産化学株式会社 2023-09-28 WO disclosed
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed
CN-115536502-A Preparation method and application of 7-methoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-30 CN disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
WO-2020255609-A1 PHOTOELECTRIC CONVERSION ELEMENT 東洋紡株式会社 2020-12-24 WO disclosed
WO-1996007656-A1 CIS-HEXAHYDRO-5-(2-NAPHTHALENYL)PYRROLO<3,4-c>PYRROLES ELI LILLY AND COMPANY (US) 1996-03-14 WO disclosed
US-5457121-A Cis-hexahydro-5-(1,2,3,4-tetrahydro-2-naphthalenyl)pyrrolo<3,4-c>pyrroles as inhibitors of serotonin reuptake ELI LILLY AND COMPANY (US) 1995-10-10 US disclosed
EP-0343830-B1 Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes LILLY CO ELI (US) 1994-07-13 EP disclosed
CN-1024665-C process for preparing ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes LILLY CO ELI (US) 1994-05-25 CN disclosed
US-5026707-A Antiserotonine agents ELI LILLY AND COMPANY (US) 1991-06-25 US disclosed
CN-1038644-A Nuclear substituted 2-amino-1,2,3,4-tetralin class LILLY CO ELI (US) 1990-01-10 CN disclosed
EP-0343830-A2 Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes ELI LILLY AND COMPANY (US) 1989-11-29 EP disclosed
US-4299636-A COMPOSITE MODIFIED DOUBLE BASE HERCULES INCORPORATED (US) 1981-11-10 US disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed
US-4115216-A QUARTERNARY AMMONIUM COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304595-A1 Electroactive Compounds NAT1, NES, SULT1E1 CYP1A2 901/4885CYP2A6 178/4885NQO1 187/4885
US-12384796-B2 Electroactive compounds NES, NAT1, SCN1B CYP1A2 944/4885CYP2A6 182/4885NQO1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.