SCHEMBL443271

SCHEMBL443271

COc1ccc2c(OC)cccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.57
CYP2A6 P11509 2/20 0.57
NQO1 P15559 1/20 0.55
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
CYP2D6 P10635 2/20 0.52
CYP1A1 P04798 5/20 0.50
CYP1B1 Q16678 5/20 0.50
RXRA P19793 1/20 0.49
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29869216 1.00 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL7453747 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL29703104 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL6939973 0.87 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL27820663 0.85 CYP1A2 (0.55) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL443625 0.84 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL30088510 0.84 CYP1A2 (0.57) CYP1A2CYP2A6NQO1BCHEACHE
SCHEMBL4600694 0.84 CYP2D6 (0.53) CYP1A2CYP2A6BCHEACHECYP2D6
SCHEMBL15772931 0.84 NQO1 (0.47) NQO1BCHEACHECYP2D6ALDH1A1
SCHEMBL15772680 0.84 NQO1 (0.47) CYP1A2CYP2A6NQO1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12051778-B2 Lithium-ion battery containing electrolyte including capacity restoration additives and method for restoring capacity of lithium-ion battery TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-07-30 US claimed
US-20220181693-A1 LITHIUM-ION BATTERY CONTAINING ELECTROLYTE INCLUDING CAPACITY RESTORATION ADDITIVES AND METHOD FOR RESTORING CAPACITY OF LITHIUM-ION BATTERY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-06-09 US claimed
CN-215568997-U Vacuum pump is used in production of 1, 6-dimethoxy naphthalene 苏州兴华高新材料科技有限公司 2022-01-18 CN claimed
CN-215542705-U Screening plant is used in production of 1, 6-dimethoxy naphthalene 苏州兴华高新材料科技有限公司 2022-01-18 CN claimed
CN-215197627-U Quick centrifugal device is used in production of 2, 5-dimethoxynaphthalene 苏州兴华高新材料科技有限公司 2021-12-17 CN claimed
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 US disclosed
US-12051778-B2 Lithium-ion battery containing electrolyte including capacity restoration additives and method for restoring capacity of lithium-ion battery TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-07-30 US disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
WO-2024024490-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2024-02-01 WO disclosed
WO-2023238920-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM TO REDUCE ENVIRONMENTAL IMPACT 日産化学株式会社 2023-12-14 WO disclosed
US-20230400770-A1 Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
US-20230400770-A1 Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
CN-1022185-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-09-22 CN disclosed
EP-0356247-B1 ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES Sankyo Company Limited (JP) 1993-03-17 EP disclosed
US-5021413-A Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
US-4931270-A Method for detecting dopaminergic diseases using fluorine-18 radiolabelled D2 dopamine receptor ligands NELSON RESEARCH & DEVELOPMENT (US) 1990-06-05 US disclosed
CN-1040791-A ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES SANKYO CO (JP) 1990-03-28 CN disclosed
EP-0356247-A1 Analgesic carboxylic acid amide derivatives Sankyo Company Limited (JP) 1990-02-28 EP disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed
US-4115216-A QUARTERNARY AMMONIUM COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CYP1A2 2381/4885CYP2A6 3213/4885NQO1 4335/4885
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CYP1A2 2381/4885CYP2A6 3213/4885NQO1 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.