Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307613 | 0.89 | F10 (0.40) | F10 | |
| SCHEMBL3307617 | 0.89 | F10 (0.40) | F10 | |
| SCHEMBL4584319 | 0.86 | F10 (0.44) | ALDH1A1HPGDCYP1A2CYP2C19F10 | |
| SCHEMBL4583142 | 0.84 | F10 (0.44) | ALDH1A1HPGDCYP1A2CYP2C19F10 | |
| SCHEMBL13372905 | 0.82 | F10 (0.33) | ALDH1A1HPGDCYP1A2CYP2C19F10 | |
| SCHEMBL4435127 | 0.80 | F10 (0.32) | ALDH1A1HPGDCYP1A2CYP2C19F10 | |
| SCHEMBL13412951 | 0.80 | ALDH1A1 (0.32) | ALDH1A1HPGDCYP1A2CYP2C19NPC1 | |
| SCHEMBL4433466 | 0.78 | F10 (0.32) | F10 | |
| SCHEMBL13372898 | 0.78 | F10 (0.33) | F10 | |
| SCHEMBL3306401 | 0.76 | F10 (0.47) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2132193-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | Boehringer Ingelheim International GmbH (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |