Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20312888 | 0.83 | CXCR3 (0.48) | CXCR3EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL26720360 | 0.81 | CXCR3 (0.43) | CXCR3EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL11514149 | 0.81 | CXCR3 (0.43) | CXCR3EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL864247 | 0.81 | CXCR3 (0.43) | CXCR3EPHX2ALDH1A1LMNA | |
| SCHEMBL8055582 | 0.81 | CXCR3 (0.43) | CXCR3EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL6938983 | 0.79 | CXCR3 (0.42) | CXCR3EPHX2ALDH1A1LMNA | |
| SCHEMBL11965856 | 0.79 | CXCR3 (0.40) | CXCR3EPHX2ALDH1A1LMNA | |
| SCHEMBL26720366 | 0.78 | CXCR3 (0.41) | CXCR3EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL27823072 | 0.78 | CXCR3 (0.44) | CXCR3EPHX2ALDH1A1LMNA | |
| SCHEMBL27767332 | 0.78 | CXCR3 (0.41) | CXCR3EPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4372014-B2 | — | — | 2009-11-25 | — | — | JP | claimed |
| US-7402576-B2 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2008-07-22 | — | — | US | claimed |
| EP-1599487-B1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | GIVAUDAN SA (CH) | 2007-07-11 | — | — | EP | claimed |
| US-20060052616-A1 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2006-03-09 | — | — | US | claimed |
| JP-2006506415-A | — | — | 2006-02-23 | — | — | JP | claimed |
| EP-1599487-A1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | Givaudan SA (CH) | 2005-11-30 | — | — | EP | claimed |
| WO-2004043971-A1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | GIVAUDAN SA (CH) | 2004-05-27 | — | — | WO | claimed |
| CN-104844679-B | The derivant of betulin | 葛兰素史克有限责任公司 | 2017-03-01 | — | — | CN | disclosed |
| US-7402576-B2 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2008-07-22 | — | — | US | disclosed |
| EP-1599487-B1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | GIVAUDAN SA (CH) | 2007-07-11 | — | — | EP | disclosed |
| US-20060052616-A1 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2006-03-09 | — | — | US | disclosed |
| EP-1599487-A1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | Givaudan SA (CH) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004043971-A1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | GIVAUDAN SA (CH) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052616-A1 | Phosphinic acid analogs of glutamate | GLUL, GRIA1, GRM1 | CXCR3 4078/4885EPHX2 1093/4885ALDH1A1 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.