Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.48 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 5/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198783 | 0.88 | GPR132 (0.52) | GPR132TBXAS1MMP9MMP8CMKLR2 | |
| SCHEMBL31734668 | 0.85 | GPR132 (0.52) | GPR132MMP9MMP8CMKLR2CMKLR1 | |
| SCHEMBL29930986 | 0.85 | ECE1 (0.51) | GPR132CMKLR2CMKLR1MMEFOLH1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL893241 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL4238049 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL27689824 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL893240 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL28142228 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL28743188 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 | |
| Alanyl-Dl-Phenylalanine SCHEMBL28127119 | 0.84 | MME (0.65) | MMEACECPA1ACE2CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531507-B2 | Acylated nonadepsipeptides containing pyridyl alanine residues | AICURIS GMBH & CO. KG (DE) | 2009-05-12 | — | — | US | disclosed |