Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 10/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL5973421 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL1147268 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL8045737 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL8186739 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL1255582 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL2783498 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL1255583 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL8868 | 0.97 | — | — | |
| Isoleucine SCHEMBL8043620 | 0.97 | SLC7A5 (0.55) | SLC7A5DPP4DPP8DPP9DPP7 | |
| Isoleucine SCHEMBL20340795 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |