Thymol

Thymol

SCHEMBL4436995

CCCCCC(=O)CC.Cc1ccc(C(C)C)c(O)c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.58
LMNA P02545 1/20 0.58
CHRM1 P11229 1/20 0.58
SLC6A2 P23975 1/20 0.58
ADRA1A P35348 1/20 0.58
HTR2B P41595 1/20 0.58
CNR1 P21554 2/20 0.44
CNR2 P34972 2/20 0.44
TRPV1 Q8NER1 1/20 0.44
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
PKM P14618 1/20 0.39
SRC P12931 1/20 0.39
NPBWR1 P48145 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MCHR1 Q99705 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymol SCHEMBL28980177 0.87 TRPA1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL27973976 0.87 LMNA (0.78) TRPA1LMNACHRM1SLC6A2ADRA1A
Stearic Acid SCHEMBL28080450 0.86 TRPA1 (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL29143213 0.86 TRPA1 (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Dodecanoate SCHEMBL17073978 0.86 TRPA1 (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL15456835 0.86 TRPA1 (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Nonanoate SCHEMBL28319012 0.86 TRPA1 (0.58) TRPA1LMNACHRM1SLC6A2ADRA1A
Undecane SCHEMBL6583325 0.85 TRPA1 (0.75) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL249974 0.83 TRPA1 (0.62) TRPA1LMNACHRM1SLC6A2ADRA1A
Thymol SCHEMBL249687 0.81 LMNA (0.72) TRPA1LMNACHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2043620-A2 COMPOSITIONS AND METHODS FOR TREATING PARASITIC INFECTIONS Tyratech, Inc. (US) 2009-04-08 EP disclosed
WO-2008003007-A2 COMPOSITIONS AND METHODS FOR TREATING PARASITIC INFECTIONS TYRATECH, INC. (US) 2008-01-03 WO disclosed