Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216090 | 0.86 | ALDH1A1 (0.37) | ALDH1A1IDO1TDO2MEN1KMT2A | |
| SCHEMBL21628044 | 0.85 | HDAC4 (0.38) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27651838 | 0.80 | ALDH1A1 (0.41) | ALDH1A1IDO1TDO2MAPK1MBTD1 | |
| SCHEMBL6692582 | 0.79 | ALDH1A1 (0.48) | ALDH1A1IDO1TDO2MAPK1HSD11B1 | |
| SCHEMBL2756356 | 0.79 | ALDH1A1 (0.48) | ALDH1A1IDO1TDO2MAPK1HSD11B1 | |
| SCHEMBL28027527 | 0.79 | GABRA1 (0.33) | — | |
| SCHEMBL1044626 | 0.79 | ALDH1A1 (0.46) | ALDH1A1IDO1TDO2MAPK1MBTD1 | |
| SCHEMBL31490296 | 0.78 | ACP3 (0.44) | ALDH1A1MAPK1NPC1CASP3SENP8 | |
| SCHEMBL9870224 | 0.78 | ACP3 (0.44) | ALDH1A1MAPK1NPC1CASP3SENP8 | |
| SCHEMBL540882 | 0.78 | ALDH1A1 (0.47) | ALDH1A1IDO1TDO2MAPK1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57002233-A | — | — | None | — | — | JP | disclosed |
| US-20250230147-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-20240300927-A1 | AMIDES AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| EP-4288428-A1 | AMIDES AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-4288429-A1 | LACTAMS AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116848106-A | Amides as CBL-B inhibitors | 基因泰克公司 | 2023-10-03 | — | — | CN | disclosed |
| US-20230079990-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2023-03-16 | — | — | US | disclosed |
| WO-2022169998-A1 | AMIDES AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022169997-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |
| JP-S572233-A | PREPARATION OF 2- 3-BENZOYLPHENYL PROPIONALDEHYDE | TAIYO YAKUHIN KOGYO KK | 1982-01-07 | — | — | JP | disclosed |
| US-4308382-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4304911-A | ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS | STERLING DRUG INC. (US) | 1981-12-08 | — | — | US | disclosed |
| US-4216326-A | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1980-08-05 | — | — | US | disclosed |
| US-4069256-A | Anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1978-01-17 | — | — | US | disclosed |
| US-4008276-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3965105-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300927-A1 | AMIDES AS CBL-B INHIBITORS | CBLB, CBL, CBLC | ALDH1A1 3896/4885IDO1 1964/4885TDO2 2974/4885 |
| US-20250230147-A1 | LACTAMS AS CBL-B INHIBITORS | CBLB, CBL, CBLC | ALDH1A1 4354/4885IDO1 2522/4885TDO2 2206/4885 |
| US-20230079990-A1 | LACTAMS AS CBL-B INHIBITORS | CBLB, CBL, CBLC | ALDH1A1 4354/4885IDO1 2522/4885TDO2 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.