Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014755 | 0.87 | RAB9A (0.66) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL23743236 | 0.84 | CYP19A1 (0.72) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL4436213 | 0.84 | SREBF2 (0.67) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| Bromide SCHEMBL8052759 | 0.83 | CYP19A1 (0.70) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL1741719 | 0.81 | CYP19A1 (0.79) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL4281217 | 0.80 | RAB9A (0.75) | CYP19A1KDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11455457 | 0.80 | RAB9A (0.75) | CYP19A1KDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11466217 | 0.79 | KDM4E (0.86) | CYP19A1KDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL196552 | 0.79 | L3MBTL1 (0.64) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL29498755 | 0.79 | L3MBTL1 (0.64) | CYP19A1KDM4ERAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120580-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS | Baylor College Of Medicine (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008097835-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS | BAYLOR COLLEGE OF MEDICINE (US) | 2008-08-14 | — | — | WO | disclosed |