Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443621 | 0.92 | TGM2 (0.30) | TGM2 | |
| SCHEMBL4437749 | 0.80 | ADRA2C (0.38) | CA1CA2 | |
| SCHEMBL3783613 | 0.73 | — | — | |
| SCHEMBL3783617 | 0.73 | — | — | |
| SCHEMBL3784409 | 0.72 | TGM2 (0.31) | TGM2 | |
| SCHEMBL3784405 | 0.72 | TGM2 (0.31) | TGM2 | |
| SCHEMBL4433088 | 0.72 | ADRA2C (0.37) | CA1CA2 | |
| SCHEMBL3780898 | 0.69 | ADRA2C (0.39) | CA1CA2 | |
| SCHEMBL3787532 | 0.68 | TGM2 (0.32) | TGM2TEAD4 | |
| SCHEMBL3787534 | 0.68 | TGM2 (0.32) | TGM2TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054411-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008013414-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2008-01-31 | — | — | WO | disclosed |