Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186978 | 0.85 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30358586 | 0.85 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24191060 | 0.85 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24191119 | 0.82 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24191374 | 0.81 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24191196 | 0.78 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5307941 | 0.77 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9328490 | 0.77 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28694001 | 0.77 | IDO1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28691199 | 0.77 | GPR84 (0.50) | HTR1AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694339-A | A kind of novel trifluoromethylthio reagent and its application | 天津科技大学 | 2019-04-30 | — | — | CN | claimed |
| CN-106748915-A | A kind of trifluoromethylthio reagent and its application | 南京理工大学 | 2017-05-31 | — | — | CN | claimed |
| CN-108863897-B | Synthesis method of trifluoromethyl thioetherified indole derivative | 天津师范大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108586312-B | Green sulfuration method of indole compound by using triphosgene as reducing agent | 丽水学院 | 2021-03-05 | — | — | CN | disclosed |
| CN-109694339-A | A kind of novel trifluoromethylthio reagent and its application | 天津科技大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-108863897-A | The synthetic method of trifluoromethyl thioetherification indole derivatives | 天津师范大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-108586312-A | It is a kind of using triphosgene as the Benzazole compounds green vulcanization process of reducing agent | 丽水学院 | 2018-09-28 | — | — | CN | disclosed |
| CN-104945304-B | Trifluoromethylthio aromatic hydrocarbons or heteroaryl hydrocarbon compound and preparation method thereof | 深圳市中科邦奇氟医学材料有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105985266-B | Trifluoromethylthio reagent, preparation method and applications | 中国科学院上海有机化学研究所 | 2018-02-16 | — | — | CN | disclosed |
| CN-106748608-A | A kind of preparation method of trifluoromethylthio substituent indole compound | 南京理工大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106748915-A | A kind of trifluoromethylthio reagent and its application | 南京理工大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106748915-A | A kind of trifluoromethylthio reagent and its application | 南京理工大学 | 2017-05-31 | — | — | CN | disclosed |
| EP-2114874-A2 | METHOD FOR PREPARING FLUORINATED SULPHANYLAMIDES AND SULPHINAMIDINES AND USES THEREOF | Aventis Pharma S.A. (FR) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008110698-A2 | METHOD FOR PREPARING FLUORINATED SULPHANYLAMIDES AND SULPHINAMIDINES AND USES THEREOF | AVENTIS PHARMA S.A. (FR) | 2008-09-18 | — | — | WO | disclosed |
| CN-1143636-A | Indoles as insecticides and acaricides | AMERICAN CYANAMID CO (US) | 1997-02-26 | — | — | CN | disclosed |
| US-5599832-A | INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5502071-A | PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0697172-A1 | Indoles as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |