Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171912 | 0.85 | ESR1 (0.43) | ESR2ESR1HDAC1KDM2BALDH1A1 | |
| SCHEMBL3171918 | 0.85 | ESR1 (0.43) | ESR2ESR1HDAC1KDM2BALDH1A1 | |
| SCHEMBL3189272 | 0.76 | ESR1 (0.43) | ESR2ESR1HDAC1KDM2B | |
| SCHEMBL3189285 | 0.76 | ESR1 (0.43) | ESR2ESR1HDAC1KDM2B | |
| SCHEMBL3178811 | 0.76 | ESR2 (0.46) | ESR2ESR1HDAC1KDM2BALDH1A1 | |
| SCHEMBL3178807 | 0.76 | ESR2 (0.46) | ESR2ESR1HDAC1KDM2BALDH1A1 | |
| SCHEMBL4563873 | 0.76 | MOGAT2 (0.54) | ESR2ESR1MOGAT2 | |
| SCHEMBL4437451 | 0.75 | HRH3 (0.53) | ESR2ESR1MOGAT2HRH3 | |
| SCHEMBL4437654 | 0.73 | MCHR1 (0.49) | ESR2ESR1HDAC1KDM2BMOGAT2 | |
| SCHEMBL4444433 | 0.73 | ESR2 (0.43) | ESR2ESR1KDM2BMOGAT2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |