Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 19/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437451 | 0.85 | HRH3 (0.53) | MOGAT2ESR1ESR2 | |
| SCHEMBL3180461 | 0.85 | GPR119 (0.44) | MOGAT2ESR1ESR2 | |
| SCHEMBL3188465 | 0.82 | MOGAT2 (0.45) | MOGAT2ESR1ESR2 | |
| SCHEMBL4437654 | 0.81 | MCHR1 (0.49) | MOGAT2ESR1ESR2 | |
| SCHEMBL4444433 | 0.81 | ESR2 (0.43) | MOGAT2ESR1ESR2 | |
| SCHEMBL4434575 | 0.80 | ESR1 (0.42) | MOGAT2ESR1ESR2 | |
| SCHEMBL3181100 | 0.77 | ESR1 (0.46) | MOGAT2ESR1ESR2 | |
| SCHEMBL4441827 | 0.76 | ESR1 (0.40) | MOGAT2ESR1ESR2 | |
| SCHEMBL4437656 | 0.76 | ESR2 (0.46) | MOGAT2ESR1ESR2 | |
| SCHEMBL3182519 | 0.75 | GPR119 (0.47) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |