Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434764 | 0.88 | MAPT (0.45) | MAPTALDH1A1RORCCA9MEN1 | |
| SCHEMBL2761698 | 0.82 | KMT2A (0.37) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL5835749 | 0.74 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28120009 | 0.73 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL2762099 | 0.71 | SMN1; SMN2 (0.45) | MAPTALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3979891 | 0.71 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3691462 | 0.71 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13086215 | 0.71 | CNR2 (0.41) | MAPTALDH1A1CA9MEN1KMT2A | |
| SCHEMBL7024513 | 0.71 | MAPT (0.40) | MAPTALDH1A1CA9MEN1KMT2A | |
| 4-Nitrobenzoic Acid SCHEMBL16053229 | 0.71 | TDP1 (0.64) | ALDH1A1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129788-B1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| EP-2129788-A2 | LUMINESCENT COMPOUNDS | Seta Biomedicals, LLC (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008094637-A2 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS. LLC (US) | 2008-08-07 | — | — | WO | disclosed |