Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437671 | 0.88 | MAPT (0.43) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL28120009 | 0.82 | ALDH1A1 (0.44) | MAPTCA1CA2CA5AALDH1A1 | |
| SCHEMBL15998115 | 0.79 | KCNH2 (0.44) | CA1CA2CA12CA9CA3 | |
| SCHEMBL13086215 | 0.77 | CNR2 (0.41) | MAPTCA2CA12CA9ALDH1A1 | |
| SCHEMBL5835749 | 0.77 | MAPT (0.73) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4443205 | 0.77 | CYP2D6 (0.44) | CA1CA2CA12CA9CA4 | |
| SCHEMBL30062268 | 0.77 | MMP14 (0.43) | MAPTALDH1A1KMT2AMEN1MMP14 | |
| SCHEMBL9347243 | 0.76 | LTA4H (0.38) | ALDH1A1KMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL168393 | 0.76 | ALDH1A1 (0.54) | MAPTCA1CA2ALDH1A1KMT2A | |
| SCHEMBL244232 | 0.76 | CNR2 (0.35) | MAPTALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626776-B | Pyrazolo[1,5-alpha] pyrimidine nitrogen mustard derivatives, preparation methods of pyrazolo[1,5-alpha] pyrimidine nitrogen mustard derivatives, and application of pyrazolo[1,5-alpha] pyrimidine nitrogen mustard derivatives in oncotherapy | 北京师范大学 | 2017-02-15 | — | — | CN | disclosed |
| EP-2129788-B1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| EP-2129788-A2 | LUMINESCENT COMPOUNDS | Seta Biomedicals, LLC (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008094637-A2 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS. LLC (US) | 2008-08-07 | — | — | WO | disclosed |