SCHEMBL4437765

SCHEMBL4437765

CCCCCCCCCCCCCCCCCCC1(CCCCCCCCCCCCCCCCCC)CCCC2(C(=O)O)OC12C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.34
PTPN1 P18031 4/20 0.31
ACP1 P24666 1/20 0.31
CDC25B P30305 1/20 0.31
GPR84 Q9NQS5 7/20 0.31
PPARG P37231 7/20 0.31
PPARD Q03181 7/20 0.31
PPARA Q07869 7/20 0.31
HDAC11 Q96DB2 5/20 0.31
TSHR P16473 4/20 0.31
ALDH1A1 P00352 2/20 0.31
TLR2 O60603 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
FABP4 P15090 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
SLC22A8 Q8TCC7 1/20 0.31
MEN1 O00255 1/20 0.31
ESR1 P03372 1/20 0.31
ALOX15 P16050 1/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1355067 1.00 SIRT2 (0.34) SIRT2PTPN1ACP1CDC25BGPR84
SCHEMBL2233452 0.71 GPR84 (0.36) PTPN1ACP1CDC25BGPR84PPARG
SCHEMBL3456829 0.71 GPR84 (0.36) PTPN1ACP1CDC25BGPR84PPARG
SCHEMBL5349789 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL9761933 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL5339781 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL2429379 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL9763148 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL5337289 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A
SCHEMBL5340532 0.71 TSHR (0.42) SIRT2TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266915-B1 THERMOPLASTIC RESIN COMPOSITIONS AND PRODUCTION PROCESSES THEREOF RIKEN TECHNOS CORP (JP) 2009-10-21 EP disclosed
US-6743860-B2 DIENE-VINYL AROMATIC BLOCK COPOLYMER CONTAINING UNIFORMLY DISPERSED ORGANIC PEROXIDE AND MULTIFUNCTIONAL VINYL OR ACRYL COMPOUND; NONGELLING EXTRUSION MOLDING MATERIAL RIKEN TECHNOS CORPORATION (JP) 2004-06-01 US disclosed
US-20030055166-A1 Thermoplastic resin compostion and poduction processes thereof RIKEN TECHNOS CORPORATION (JP) 2003-03-20 US disclosed
EP-1266915-A1 THERMOPLASTIC RESIN COMPOSITIONS AND PRODUCTION PROCESSES THEREOF Riken Technos Corporation (JP) 2002-12-18 EP disclosed