SCHEMBL4438

SCHEMBL4438

O=S(=O)(Cl)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.58
CA1 P00915 2/20 0.58
PRSS1 P07477 2/20 0.58
PRSS2 P07478 2/20 0.58
PRSS3 P35030 2/20 0.58
FAAH O00519 1/20 0.58
ELANE P08246 1/20 0.58
PRTN3 P24158 1/20 0.58
CA5A P35218 1/20 0.58
CA9 Q16790 1/20 0.58
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
KMT2A Q03164 3/20 0.50
HSP90AA1 P07900 1/20 0.47
F2 P00734 1/20 0.47
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26129401 0.97 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
Fluoride SCHEMBL27921338 0.97 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL2349436 0.97 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
Water SCHEMBL21268700 0.97 CA2 (0.56) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL8166600 0.86 ABCC4 (0.47) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL7243419 0.86 CA2 (0.40) CA2CA1PRSS1PRSS2PRSS3
Phosphine SCHEMBL28632778 0.85 TDP1 (0.46) CA2CA1PRSS1PRSS2PRSS3
Formic Acid Methyl Ester SCHEMBL28442612 0.84 PRSS1 (0.48) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL29042672 0.82 HPGD (0.45) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL27461229 0.82 TXNRD1 (0.52) CA2CA1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13743 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097873-A1 HALOGENATED INDOLINONE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF, HALOGENATED INDOLINONE DERIVATIVE AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 广州湾区生物医药研究院 2026-05-15 WO claimed
EP-3980396-B1 PRODUCING LONG CHAIN AMINO AND DIBASIC ACIDS VITAWORKS IP LLC (US) 2025-10-08 EP claimed
US-20250296924-A1 PROCESS FOR PRODUCING POLYHYDROXY ESTERS OF NICOTINIC ACID BioHope (Suzhou) Pharmatech Co., Ltd (CN) 2025-09-25 US claimed
EP-4590769-A2 LIGNIN-BASED BIODEGRADABLE POLYMERS AND METHODS OF MAKING THE SAME The Florida State University Research Foundation, Inc. (US) 2025-07-30 EP claimed
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 EP claimed
EP-4577528-A1 PREPARATION OF A P2X3 ANTAGONIST 14245563 Canada Inc. (CA) 2025-07-02 EP claimed
CN-118221794-B Vegetable protein and application thereof in preparation of liquid enzyme protective agent 浙江理工大学 2025-04-25 CN claimed
WO-2025083736-A1 NOVEL PROCESS FOR THE PREPARATION OF PIRTOBRUTINIB AND ITS INTERMEDIATES THEREOF MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2025-04-24 WO claimed
CN-119565410-A Seawater desalination reverse osmosis membrane, preparation method and application 湖南澳维膜科技有限公司 2025-03-07 CN claimed
CN-119371338-A Preparation method of benzyl sulfonyl chloride 寿光诺盟化工有限公司 2025-01-28 CN claimed
EP-0061840-A2 Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-10-06 EP claimed
EP-0061760-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed
EP-0061761-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed
US-4337336-A Derivative of kanamycin A and a process for the preparation thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-06-29 US claimed
EP-0044940-A1 Amino-desoxy-1.4;3.6-dianhydro-hexite nitrates, processes for their preparation and pharmaceutical compositions Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP claimed
EP-0044931-A1 2-0 and 5-0-Substituted 1,4;3,6-dianhydro-hexite mononitrates, processes for their preparation and pharmaceutical preparations Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP claimed
EP-0044932-A1 Optionally N-substituted amino-deoxy-1,4;3,6-dianhydro-hexite derivatives, processes for their preparation and their application Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP claimed
EP-0044927-A1 Alkylamino-desoxy-1,4;3,6-dianhydro-hexite-nitrate substituted by purine bases, process for their preparation and their pharmaceutical compositions Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP claimed
EP-0044928-A1 1,4;3,6-Dianhydro-hexite-nitrate substituted by purine bases, process for their preparation and their pharmaceutical compositions Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-03 EP claimed
US-4207200-A Soluble complex former for the affinity specific separation of macromolecular substances, its preparation and its use BUNEMANN HANS (DE) 1980-06-10 US claimed