SCHEMBL443820

SCHEMBL443820

c1ccc2cc(Oc3cccc4ccccc34)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.61
RCE1 Q9Y256 1/20 0.61
MAPT P10636 4/20 0.49
LMNA P02545 3/20 0.49
HTT P42858 3/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
CYP2A6 P11509 2/20 0.47
CYP1A2 P05177 1/20 0.47
HAO1 Q9UJM8 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MITF O75030 1/20 0.46
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KCNA3 P22001 1/20 0.44
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30731587 1.00 GAA (0.61) GAARCE1MAPTLMNAHTT
SCHEMBL28440233 0.94 GAA (0.55) GAARCE1MAPTLMNAHTT
SCHEMBL7457094 0.88 KCNA3 (0.52) GAARCE1MAPTLMNAHTT
SCHEMBL2078871 0.87 L3MBTL1 (0.54) GAARCE1MAPTLMNAHTT
SCHEMBL28440234 0.86 GAA (0.59) GAARCE1MAPTLMNAHTT
SCHEMBL13829442 0.85 ESR1 (0.47) GAARCE1MAPTLMNAHTT
SCHEMBL13829351 0.85 ESR1 (0.47) GAARCE1MAPTLMNAHTT
SCHEMBL7203253 0.85 CYP1A2 (0.66) GAARCE1MAPTLMNAHTT
SCHEMBL28188294 0.84 HPRT1 (0.56) GAARCE1MAPTLMNAHTT
SCHEMBL14243918 0.83 CYP1A2 (0.55) GAARCE1MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116841-A1 DINAPHTHYL ETHER COMPOUND AND LUBRICANT COMPOSITIONCONTAINING SAME MORESCO CORPORATION (JP) 2024-04-11 US disclosed
EP-4273118-A1 DINAPHTHYL ETHER COMPOUND AND LUBRICANT COMPOSITION CONTAINING SAME Moresco Corporation (JP) 2023-11-08 EP disclosed
CN-117015522-A Dinaphthyl ether compound and lubricating oil composition containing the same 株式会社MORESCO 2023-11-07 CN disclosed
CN-111777731-B Modified naphthalene water reducer with high slump loss resistance and preparation method thereof 安徽鑫固环保股份有限公司 2023-07-25 CN disclosed
CN-111825364-B Preparation method of environment-friendly naphthalene water reducer 安徽鑫固环保股份有限公司 2022-06-14 CN disclosed
CN-111825364-A Preparation method of environment-friendly naphthalene water reducer 安徽鑫固环保股份有限公司 2020-10-27 CN disclosed
CN-111808651-A 2-naphthol distillation residue modified coal water slurry dispersing agent and preparation method thereof 萧县沃德化工科技有限公司 2020-10-23 CN disclosed
CN-111807738-A Additive for geopolymer 安徽鑫固环保股份有限公司 2020-10-23 CN disclosed
CN-111808641-A Novel water-coal-slurry dispersant and preparation method thereof 萧县沃德化工科技有限公司 2020-10-23 CN disclosed
CN-111792868-A Environment-friendly naphthalene-based high-efficiency water reducing agent and preparation method thereof 萧县沃德化工科技有限公司 2020-10-20 CN disclosed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US disclosed
US-5739372-A CYCLIZATION AT THE HYDROXY POSITION OF AN ORTHO PHENYL OR NAPHTHYL SUBSTITUTED PHENOL OR NAPHTHOL WITH A PHOSPHORUS CHLORIDE OR BROMIDE IN THE PRESENCE OF A LEWIS ACID CATALYST WITH THE ELIMINATION OF HYDROGEN CHLORIDE OR BROMIDE HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
EP-0748812-A1 Novel oxaphosphorines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-18 EP disclosed
EP-0307993-B1 COMPOSITES COMPRISING AN ARAMID MATRIX AKZO N.V. (NL) 1992-04-01 EP disclosed
US-5010168-A Heat and chemical stability AKZO NV (NL) 1991-04-23 US disclosed
US-4908264-A Composites comprising an aramid matrix AKZO N.V. (NL) 1990-03-13 US disclosed
EP-0307993-A1 Composites comprising an aramid matrix AKZO N.V. (NL) 1989-03-22 EP disclosed
US-4546139-A FIRE RETARDANT ADDITIVE TO POLYMERS PPG INDUSTRIES, INC. (US) 1985-10-08 US disclosed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116841-A1 DINAPHTHYL ETHER COMPOUND AND LUBRICANT COMPOSITIONCONTAINING SAME DERL1, UBE2L3, C9 GAA 4618/4885RCE1 3636/4885MAPT 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.