Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441491 | 0.89 | RECQL (0.33) | GPR119 | |
| SCHEMBL4427892 | 0.73 | CRBN (0.34) | GPR119 | |
| SCHEMBL8313985 | 0.71 | NPC1 (0.36) | — | |
| SCHEMBL2467200 | 0.71 | — | — | |
| SCHEMBL7527330 | 0.68 | MAPT (0.41) | — | |
| SCHEMBL8137468 | 0.68 | MAPK1 (0.33) | — | |
| SCHEMBL7261773 | 0.68 | CYP11B1 (0.38) | GPR119 | |
| SCHEMBL31701242 | 0.67 | GRM1 (0.55) | GPR119 | |
| SCHEMBL64945 | 0.67 | GRM1 (0.55) | GPR119 | |
| SCHEMBL7014119 | 0.67 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125748-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | AstraZeneca AB (SE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008075068-A2 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |