SCHEMBL4438736

SCHEMBL4438736

NC(=O)OC(=O)OC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
OR51E2 Q9H255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ACHE P22303 1/20 0.36
CA4 P22748 3/20 0.35
ALOX15 P16050 2/20 0.35
CA1 P00915 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663113 0.96 LMNA (0.36) LMNAALDH1A1OR51E2TDP1ACHE
Ammonia Solution, Strong SCHEMBL10618980 0.96 LMNA (0.36) LMNAALDH1A1OR51E2TDP1ACHE
SCHEMBL3359099 0.87 ACHE (0.35) ACHELDHALDHB
SCHEMBL30671765 0.84 ACHE (0.33) ACHELDHALDHB
SCHEMBL228466 0.82
SCHEMBL6743655 0.82
SCHEMBL28768793 0.79
Ammonia Solution, Strong SCHEMBL17223995 0.78
SCHEMBL10425379 0.78
Ammonia Solution, Strong SCHEMBL453946 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150328230-A1 CLEARANCE OF AMYLOID BETA SYNAPTEC DEVELOPMENT LLC (US) 2015-11-19 US claimed
JP-56040658-A None JP disclosed
CN-117466939-A Long-acting prodrug derivative for controlling in-vivo drug release 烟台药物研究所 2024-01-30 CN disclosed
US-11812741-B2 Method for producing a biocide A.Y. LABORATORIES LTD. (IL) 2023-11-14 US disclosed
EP-3665168-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES Nouryon Chemicals International B.V. (NL) 2020-06-17 EP disclosed
WO-2019030197-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2019-02-14 WO disclosed
US-9272242-B2 High cyclic capacity amines for high efficiency CO2 scrubbing processes EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-03-01 US disclosed
US-20140030177-A1 HIGH CYCLIC CAPACITY AMINES FOR HIGH EFFICIENCY CO2 SCRUBBING PROCESSES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-01-30 US disclosed
CN-102177213-A Adhesive laminate ASAHI GLASS CO LTD 2011-09-07 CN disclosed
EP-2115084-A2 METHOD FOR PREPARING POLYHYDROXY-URETHANES Rhodia Opérations (FR) 2009-11-11 EP disclosed
WO-2008107568-A2 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2008-09-12 WO disclosed
EP-1045875-A1 HARD FOAMED PLASTIC MOULDED BODIES WITH A COMPACT OUTER SKIN Henkel Kommanditgesellschaft auf Aktien (DE) 2000-10-25 EP disclosed
WO-1999032545-A1 HARD FOAMED PLASTIC MOULDED BODIES WITH A COMPACT OUTER SKIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-07-01 WO disclosed
US-5151405-A Multilayer element of a support and a modified dextran binder AGFA-GEVAERT, N.V. (BE) 1992-09-29 US disclosed
JP-S5640658-A AROMATIC CARBAMATE CARBONATE AND ITS PREPARATION MITSUI TOATSU CHEM INC 1981-04-16 JP disclosed
US-3965168-A CITRIC ACID INTERMEDIATE ETHYL CORPORATION (US) 1976-06-22 US disclosed
US-3960941-A CHEMICAL INTERMEDIATE FOR CITRIC ACID ETHYL CORPORATION (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150328230-A1 CLEARANCE OF AMYLOID BETA BACE1, APP, BCHE LMNA 1900/4885ALDH1A1 1860/4885OR51E2 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.