⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639641 | 0.85 | HDAC3 (0.33) | — | |
| SCHEMBL1512247 | 0.77 | — | — | |
| Dimethylamine SCHEMBL10861087 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL536155 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL4440371 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL3286238 | 0.72 | — | — | |
| SCHEMBL1880926 | 0.72 | HDAC3 (0.31) | — | |
| SCHEMBL749123 | 0.71 | — | — | |
| SCHEMBL261066 | 0.71 | — | — | |
| Methacrylic Acid SCHEMBL27551279 | 0.70 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353236-A1 | COMPOUND AND METHOD FOR TREATING CHEMOTHERAPY-RELATED GASTROINTESTINAL SIDE EFFECTS | OnQuality Pharmaceuticals China Ltd. (CN) | 2024-04-17 | — | — | EP | disclosed |
| EP-4353231-A1 | COMPOUND AND METHOD FOR TREATING CHEMOTHERAPY-ASSOCIATED GASTROINTESTINAL SIDE EFFECTS | OnQuality Pharmaceuticals China Ltd. (CN) | 2024-04-17 | — | — | EP | disclosed |
| EP-2137188-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Pharma AG (DE) | 2012-06-06 | — | — | EP | disclosed |
| EP-2137188-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008113469-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-25 | — | — | WO | disclosed |
| US-6303289-B1 | Composition and methods for the treatment of cancer and viral infections | ELENOR ROOSEVELT INSTITUTE | 2001-10-16 | — | — | US | disclosed |
| US-20010029012-A1 | Composition and methods for the treatment of cancer and viral infections | ELEANOR ROOSEVELT INSTITUTE | 2001-10-11 | — | — | US | disclosed |
| WO-2000056158-A1 | COMPOSITION AND METHODS FOR THE TREATMENT OF CANCER AND VIRAL INFECTIONS | ELEANOR ROOSEVELT INSTITUTE (US) | 2000-09-28 | — | — | WO | disclosed |