Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6626174 | 0.98 | KCNN4 (0.38) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL11661542 | 0.79 | MAPK1 (0.44) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL21637586 | 0.76 | MAPK1 (0.41) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL89308 | 0.75 | KCNN4 (0.44) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL15434945 | 0.75 | KCNN4 (0.44) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL487295 | 0.74 | MAPK1 (0.43) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL20394562 | 0.73 | MAPK1 (0.39) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL14461649 | 0.73 | MAPK1 (0.39) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL14154663 | 0.72 | KCNN4 (0.41) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 | |
| SCHEMBL11192903 | 0.69 | CYP2D6 (0.48) | KCNN4MAPK1ALOX15ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114919-A2 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPERATION | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-11-11 | — | — | EP | claimed |
| WO-2008092939-A2 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPARATION | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2008-08-07 | — | — | WO | claimed |
| US-20200269668-A1 | Biologically Efficacious Compositions, Articles of Manufacture And Processes For Producing And/Or Using Same | VACHON DAVID JOHN (US) | 2020-08-27 | — | — | US | disclosed |
| US-20170304815-A1 | Antimicrobial And Biological Active Polymer Composites And Related Methods, Materials and Devices | VACHON DAVID JOHN (US) | 2017-10-26 | — | — | US | disclosed |
| EP-3190881-A1 | ANTIMICROBIAL AND BIOLOGICALLY ACTIVE POLYMER COMPOSITES AND RELATED METHODS, MATERIALS AND DEVICES | Iasis Molecular Sciences (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016040529-A1 | ANTIMICROBIAL AND BIOLOGICALLY ACTIVE POLYMER COMPOSITES AND RELATED METHODS, MATERIALS AND DEVICES | IASIS MOLECULAR SCIENCES (US) | 2016-03-17 | — | — | WO | disclosed |
| US-20140099357-A1 | Biologically Efficacious Compositions, Articles of Manufacture and Processes for Producing and/or Using Same | Iasis Molecular Sciences LLC (US) | 2014-04-10 | — | — | US | disclosed |
| US-20130004586-A1 | Biologically Efficacious Compositions, Articles of Manufacture and Processes for Producing and/or Using Same | VACHON DAVID J (US) | 2013-01-03 | — | — | US | disclosed |
| EP-2537415-A1 | Biologically efficacious compositions, articles of manufacture and processes for producing and/or using same | Vachon, David (US) | 2012-12-26 | — | — | EP | disclosed |
| EP-2114919-A2 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPERATION | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008092939-A2 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPARATION | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2008-08-07 | — | — | WO | disclosed |
| US-6077822-A | COMPRISING WATER-INSOLUBLE SALT OF MONO TO OCTA-SACCHARIDE SUGAR ACID WITH BIOLOGICALLY ACTIVE COMPOUND SELECTED FROM AMINOGLYCOSIDES, TETRACYCLINES, POLYPEPTIDES, GLYCOPEPTIDES AND MACROLIDES FOR CONTROLLED RELEASE OF DRUGS | DUMEX-ALPHARMA A/S (DK) | 2000-06-20 | — | — | US | disclosed |
| EP-0764169-B1 | DRUG SALTS | DUMEX LTD AS (DK) | 1998-09-23 | — | — | EP | disclosed |
| EP-0764169-A2 | DRUG SALTS | DUMEX-ALPHARMA A/S (DK) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034571-A2 | DRUG SALTS | DUMEX ALPHARMA A/S (DK) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304815-A1 | Antimicrobial And Biological Active Polymer Composites And Related Methods, Materials and Devices | PHOSPHO1, PGLS, PUF60 | KCNN4 99/4885MAPK1 613/4885ALOX15 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.