Chlorobenzene

Chlorobenzene

SCHEMBL4439009

Clc1ccccc1.c1ccc2c(c1)CCCC2

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
AVPR2 P30518 1/20 0.42
AVPR1A P37288 1/20 0.42
CYP1A2 P05177 1/20 0.42
SIGMAR1 Q99720 3/20 0.40
HTR2C P28335 1/20 0.40
HPGD P15428 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11299980 0.86 TSHR (0.93) TSHRSIGMAR1HTR2CHPGDL3MBTL1
Hydrogen Peroxide SCHEMBL30110573 0.83 TSHR (0.87) TSHRMEN1KMT2ASIGMAR1HTR2C
Benzene SCHEMBL6406426 0.83 TSHR (0.87) TSHRSIGMAR1HTR2CHPGDL3MBTL1
Hydrogen Peroxide SCHEMBL298462 0.83 TSHR (0.87) TSHRMEN1KMT2ASIGMAR1HTR2C
SCHEMBL29358070 0.83 TSHR (1.00) TSHRSIGMAR1HTR2CHPGDL3MBTL1
SCHEMBL385555 0.83 TSHR (1.00) TSHRSIGMAR1HTR2CHPGDL3MBTL1
SCHEMBL11645158 0.83 TSHR (1.00) TSHRSIGMAR1HTR2CHPGDL3MBTL1
SCHEMBL8355 0.83 TSHR (1.00) TSHRSIGMAR1HTR2CHPGDL3MBTL1
SCHEMBL11606739 0.83 TSHR (1.00) TSHRSIGMAR1HTR2CHPGDL3MBTL1
SCHEMBL25404307 0.80 TSHR (0.93) TSHRSIGMAR1HTR2CHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6888036-B2 Mono-and polybenzyl-1,2,3,4-tetrahydronaphthalene compositions, use of said compositions or mixture of monobenzyl-,1,2,3,4-tetrahydronaphthalene as heat transfer fluid ARKEMA (FR) 2005-05-03 US claimed
US-20040077907-A1 Mono-and polybenzyl-1,2,3,4-tetrahydronaphthalene compositions, use of said compositions or mixture of monobenzyl-,1,2,3,4-tetrahydronaphthalene as heat transfer fluid ATOFINA (FR) 2004-04-22 US claimed
EP-1268374-B1 MONO- AND POLYBENZYL-1,2,3,4-TETRAHYDRONAPHTHALENE COMPOSITIONS, USE OF SAID COMPOSITIONS OR MIXTURE OF MONOBENZYL-1,2,3,4-TETRAHYDRONAPHTHALENE ISOMERS AS HEAT TRANSFER FLUID ATOFINA (FR) 2003-11-05 EP claimed
EP-2086034-A1 Electronic device and method of manufacturing thereof Nederlandse Centrale Organisatie Voor Toegepast Natuurwetenschappelijk Onderzoek TNO (NL) 2009-08-05 EP disclosed
US-20080160344-A1 Wet processing; thin films; electrolytic cells IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-7357991-B2 Mixture of electroluminescent compound and solvent; electrolytic cells IDEMITSU KOSAN CO., LTD. (JP) 2008-04-15 US disclosed
US-20050014017-A1 Mixture of electroluminescent compound and solvent; electrolytic cells IDEMITSU KOSAN CO., LTD. (JP) 2005-01-20 US disclosed
EP-1440959-A1 NOVEL SOLUBLE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2004-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160344-A1 Wet processing; thin films; electrolytic cells EPCAM, L1CAM, IWS1 TSHR 4410/4885MEN1 2905/4885KMT2A 2548/4885
US-20040077907-A1 Mono-and polybenzyl-1,2,3,4-tetrahydronaphthalene compositions, use of said compositions or mixture of monobenzyl-,1,2,3,4-tetrahydronaphthalene as heat transfer fluid BPNT1, ABCB11, CYP1B1 TSHR 4822/4885MEN1 268/4885KMT2A 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.