Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184635 | 0.86 | HTT (0.50) | HTTKMT2ALMNAUSP7ESR1 | |
| SCHEMBL13531824 | 0.74 | ESR1 (0.42) | HTTKMT2ALMNAESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3181917 | 0.73 | ESR1 (0.42) | HTTKMT2ALMNAESR1ESR2 | |
| SCHEMBL2901525 | 0.73 | POLB (0.60) | HTTKMT2ALMNAUSP7HTR4 | |
| SCHEMBL3186533 | 0.72 | S1PR1 (0.47) | ESR1ESR2KDM2B | |
| SCHEMBL26187340 | 0.72 | HTT (0.67) | HTTKMT2ALMNAUSP7KDM4E | |
| SCHEMBL3181559 | 0.72 | GPR119 (0.40) | ESR1ESR2GPR119KDM2B | |
| SCHEMBL2900452 | 0.72 | NPC1 (0.57) | HTTKMT2ALMNAUSP7HTR4 | |
| SCHEMBL13135846 | 0.72 | USP7 (0.55) | HTTKMT2ALMNAUSP7HTR4 | |
| Hydrochloric Acid SCHEMBL3828123 | 0.72 | HTR4 (0.59) | HTTKMT2ALMNAUSP7HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | claimed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | claimed |