Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135606 | 0.79 | — | — | |
| SCHEMBL513742 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| Biphenyl SCHEMBL27813018 | 0.70 | ALDH1A1 (0.64) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL5261071 | 0.69 | KDM4E (0.48) | ALDH1A1SMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL1747905 | 0.66 | ALDH1A1 (0.47) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL490962 | 0.66 | ALDH1A1 (0.47) | ALDH1A1TAAR1SMN1; SMN2MAPK1NR1H4 | |
| Biphenyl SCHEMBL27643334 | 0.59 | ALDH1A1 (0.82) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 | |
| Biphenyl SCHEMBL2548048 | 0.58 | ALDH1A1 (1.00) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL29560186 | 0.58 | ALDH1A1 (1.00) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 | |
| Biphenyl SCHEMBL1358618 | 0.58 | ALDH1A1 (1.00) | ALDH1A1TAAR1SMN1; SMN2MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090107908-A1 | Thermally, Heat and Chemically Resistant Ultrafiltration Polyimide Membrane and Method for its Production | POLOTSKAYA GALINA A | 2009-04-30 | — | — | US | claimed |
| US-5874477-A | ADMINISTERING AN AMINOTETRALIN, A PHENYL DIOXIN, A AN ERGOLINE, AN INDOLE DERIVATIVE OR AN ALKYLPIPERIDINE, PRECURSORS OF WHICH ARE FRUIT PEELINGS; DISPLACEMENT OF LIGANDS ON SUBTYPE 5HT1A OR 5HT2/5HT1C; REDUCE SYMPTOMS | THE UNIVERSITY OF HAWAII (US) | 1999-02-23 | — | — | US | claimed |
| WO-1996004898-A1 | A METHOD OF TREATMENT FOR MALARIA | MCCONNELL BRUCE (US) | 1996-02-22 | — | — | WO | claimed |
| US-9812315-B2 | Treating solution for electronic parts, and process for producing electronic parts | FINE POLYMERS CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-9812315-B2 | Treating solution for electronic parts, and process for producing electronic parts | FINE POLYMERS CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-9812315-B2 | Treating solution for electronic parts, and process for producing electronic parts | FINE POLYMERS CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| CN-104487840-B | Method for fractionating dioxins | 三浦工业株式会社 | 2017-09-12 | — | — | CN | disclosed |
| US-20150279654-A1 | TREATING SOLUTION FOR ELECTRONIC PARTS, AND PROCESS FOR PRODUCING ELECTRONIC PARTS | FINE POLYMERS CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150279654-A1 | TREATING SOLUTION FOR ELECTRONIC PARTS, AND PROCESS FOR PRODUCING ELECTRONIC PARTS | FINE POLYMERS CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150279654-A1 | TREATING SOLUTION FOR ELECTRONIC PARTS, AND PROCESS FOR PRODUCING ELECTRONIC PARTS | FINE POLYMERS CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| CN-203586219-U | Cremation machine with built-in four-time combustion chamber | JIN ZHIPING | 2014-05-07 | — | — | CN | disclosed |
| US-20140051664-A1 | COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH RADIOTHERAPY | SYNTA PHARMACEUTICALS CORP. (US) | 2014-02-20 | — | — | US | disclosed |
| CN-101378993-B | Method for the preparation of aqueous dispersions of TiO2 in the form of nanoparticles, and dispersions obtainable with this method | COLOROBBIA ITALIANA SPA | 2012-11-07 | — | — | CN | disclosed |
| US-20120234750-A1 | THERMALLY, HEAT AND CHEMICALLY RESISTANT ULTRAFILTRATION POLYIMIDE MEMBRANE AND METHOD FOR ITS PRODUCTION | POLOTSKAYA GALINA A (US) | 2012-09-20 | — | — | US | disclosed |
| US-20090107908-A1 | Thermally, Heat and Chemically Resistant Ultrafiltration Polyimide Membrane and Method for its Production | POLOTSKAYA GALINA A | 2009-04-30 | — | — | US | disclosed |
| CN-2386329-Y | Incinerator with built-in tertiary combustion chamber | ZHAO GUOCHAO (CN) | 2000-07-05 | — | — | CN | disclosed |
| US-5874477-A | ADMINISTERING AN AMINOTETRALIN, A PHENYL DIOXIN, A AN ERGOLINE, AN INDOLE DERIVATIVE OR AN ALKYLPIPERIDINE, PRECURSORS OF WHICH ARE FRUIT PEELINGS; DISPLACEMENT OF LIGANDS ON SUBTYPE 5HT1A OR 5HT2/5HT1C; REDUCE SYMPTOMS | THE UNIVERSITY OF HAWAII (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1996004898-A1 | A METHOD OF TREATMENT FOR MALARIA | MCCONNELL BRUCE (US) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051664-A1 | COMBINATION THERAPY OF HSP90 INHIBITORY COMPOUNDS WITH RADIOTHERAPY | HSP90AB1, HSP90AA1, HSP90B1 | ALDH1A1 3008/4885TAAR1 4188/4885SMN1; SMN2 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.