Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.42 |
| ▸ | PGR | P06401 | 10/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442637 | 0.72 | NR3C1 (0.41) | NR3C1NR3C2PGR | |
| SCHEMBL14159634 | 0.70 | NR3C1 (0.34) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL4823422 | 0.69 | NR3C1 (0.52) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL1492612 | 0.68 | NR3C1 (0.56) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL1723315 | 0.68 | NR3C1 (0.56) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL4442883 | 0.68 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL1492536 | 0.68 | NR3C1 (0.48) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL5776633 | 0.67 | NR3C1 (0.43) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL5779656 | 0.65 | NR3C1 (0.46) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL5355518 | 0.64 | NR3C1 (0.43) | NR3C1NR3C2PGRPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |