Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.39 |
| ▸ | PGR | P06401 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159634 | 0.84 | NR3C1 (0.34) | NR3C1NR3C2PGR | |
| SCHEMBL4167085 | 0.74 | CYP1A2 (0.42) | NR3C1NR3C2PGRCYP1A2HTR2A | |
| SCHEMBL4150281 | 0.72 | PDE4B (0.38) | NR3C1NR3C2PGRCYP1A2HTR2A | |
| SCHEMBL6384571 | 0.69 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL292631 | 0.68 | NR3C1 (0.49) | NR3C1NR3C2PGRCYP1A2HTR2A | |
| SCHEMBL4439166 | 0.68 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL6382647 | 0.67 | NR3C1 (0.46) | NR3C1NR3C2PGRCYP1A2HTR2A | |
| SCHEMBL6383344 | 0.67 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL7082910 | 0.62 | PDE4B (0.48) | CYP1A2HTR2AHTR2CHTR2BCYP11B2 | |
| SCHEMBL3656890 | 0.62 | NR3C1 (0.62) | NR3C1NR3C2PGRERN1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |