Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907266 | 0.89 | MEN1 (0.86) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL28045887 | 0.85 | CYP19A1 (0.78) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL1068874 | 0.84 | PLK1 (0.67) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL28513250 | 0.84 | MEN1 (0.74) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL665265 | 0.84 | CYP19A1 (0.84) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL27715512 | 0.80 | PLK1 (0.68) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL29204369 | 0.80 | NPC1 (0.67) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL9063227 | 0.80 | CYP19A1 (0.70) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL3364494 | 0.80 | MEN1 (0.65) | CYP19A1POLBMEN1MAPTKMT2A | |
| SCHEMBL17907269 | 0.79 | MEN1 (0.67) | CYP19A1POLBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429602-B1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | UNIV RUTGERS (US) | 2009-12-16 | — | — | EP | disclosed |
| EP-1429602-A4 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | UNIV RUTGERS (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6893627-B2 | Method for treating type 2 diabetes with an extract of Artemisia | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2005-05-17 | — | — | US | disclosed |
| US-20050069598-A1 | Methods for treating disorders using plant extracts | RIBNICKY DAVID M (US) | 2005-03-31 | — | — | US | disclosed |
| EP-1429602-A1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030072822-A1 | Methods for treating disorders using plant extracts | RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY | 2003-04-17 | — | — | US | disclosed |
| WO-2003020026-A1 | METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2003-03-13 | — | — | WO | disclosed |