SCHEMBL17907266

SCHEMBL17907266

COc1cc(O)c2c(c1O)OC(c1ccccc1)CC2=O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.86
MAPT P10636 2/20 0.86
KMT2A Q03164 2/20 0.86
POLB P06746 2/20 0.86
GAA P10253 1/20 0.86
PABPC1 P11940 1/20 0.86
APEX1 P27695 1/20 0.86
RECQL P46063 1/20 0.86
EIF4H Q15056 1/20 0.86
L3MBTL1 Q9Y468 1/20 0.86
CYP19A1 P11511 2/20 0.80
ABCG2 Q9UNQ0 5/20 0.65
ABCB1 P08183 2/20 0.65
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
HSD17B10 Q99714 3/20 0.58
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 2/20 0.58
CYP3A4 P08684 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173021 0.90 MAPT (0.70) MEN1MAPTKMT2APOLBGAA
SCHEMBL4439740 0.89 CYP19A1 (0.74) MEN1MAPTKMT2APOLBGAA
SCHEMBL28045887 0.89 CYP19A1 (0.78) MEN1MAPTKMT2APOLBGAA
SCHEMBL28513250 0.85 MEN1 (0.74) MEN1MAPTKMT2APOLBGAA
SCHEMBL665265 0.85 CYP19A1 (0.84) MEN1MAPTKMT2APOLBGAA
SCHEMBL27715512 0.84 PLK1 (0.68) MEN1MAPTKMT2APOLBGAA
SCHEMBL9063227 0.84 CYP19A1 (0.70) MEN1MAPTKMT2APOLBGAA
SCHEMBL28823056 0.82 MAPT (0.82) MEN1MAPTKMT2APOLBGAA
SCHEMBL31238503 0.81 CYP19A1 (0.67) MEN1MAPTKMT2APOLBGAA
SCHEMBL29895534 0.81 CYP3A4 (0.79) MEN1MAPTKMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042897-B1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY AGENT, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING THE COMPOUND AMINO UP CO LTD (JP) 2019-09-11 EP disclosed
US-9573920-B2 Compound, medicine, anti-inflammatory, cosmetic, food and drink, and method for producing compound AMINO UP CHEMICAL CO., LTD (JP) 2017-02-21 US disclosed
US-9573920-B2 Compound, medicine, anti-inflammatory, cosmetic, food and drink, and method for producing compound AMINO UP CHEMICAL CO., LTD (JP) 2017-02-21 US disclosed
US-20160207901-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND Amino Up Co., Ltd. (JP) 2016-07-21 US disclosed
US-20160207901-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND Amino Up Co., Ltd. (JP) 2016-07-21 US disclosed
EP-3042897-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND Amino Up Chemical Co., Ltd. (JP) 2016-07-13 EP disclosed
CN-105492431-A Compound, medicine, anti-inflammatory, cosmetic, food and drink, and method for producing compound AMINO UP CHEMICAL CO LTD 2016-04-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160207901-A1 COMPOUND, MEDICINE, ANTI-INFLAMMATORY, COSMETIC, FOOD AND DRINK, AND METHOD FOR PRODUCING COMPOUND MPO, TNF, CUTA MEN1 201/4885MAPT 1946/4885KMT2A 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.