SCHEMBL4440197

SCHEMBL4440197

C=C(CN1CCCC1)[C@@H]1CC[C@]2(C(=O)NCCc3cccc(C(=O)NCc4ccc(C(=O)O)cn4)c3)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 16/20 0.53
▸ TRPV1 Q8NER1 1/20 0.46
▸ EGLN2 Q96KS0 1/20 0.42
▸ EGLN1 Q9GZT9 1/20 0.42
▸ EGLN3 Q9H6Z9 1/20 0.42
▸ P4HTM Q9NXG6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13628310 0.91 RORC (0.58) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL4453635 0.91 TRPV1 (0.51) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL4447638 0.89 RORC (0.49) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL4445786 0.88 RORC (0.48) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL4449841 0.88 RORC (0.46) RORCTRPV1
SCHEMBL4451644 0.86 RORC (0.48) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL4451635 0.86 RORC (0.48) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL13637471 0.86 RORC (0.48) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL13628623 0.86 RORC (0.48) RORCTRPV1EGLN2EGLN1EGLN3
SCHEMBL13637654 0.85 RORC (0.42) RORCTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MYRIAD GENETICS, INCORPORATED (US) 2009-11-05 — — US disclosed
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MYRIAD GENETICS, INCORPORATED (US) 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MAVS, ZC3HAV1, EIF2AK2 RORC 514/4885TRPV1 3411/4885EGLN2 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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